Vitamin D: Nutrient, Hormone, and Immunomodulator

Vitamin D: the iceberg nutrient.

The understanding of vitamin D's role in human health has recently expanded. It is now recognized as more than a hormone activated in the kidney only for calcium homeostasis. It is metabolized and used by virtually every cell in the body. Patients with chronic kidney disease have a deficit in their kidney production of 1,25(OH)(2)D and have classically been treated with calcitriol or its active...

Parathyroid hormone and vitamin D.

Along with many others of my generation at the Yale School of Medicine and the New Haven Hospital, I owe a great debt to Grover Powers as an inspiring teacher, friend, and benefactor. The invitation to give the Grover Powers lecture at Yale had a special emotional significance, therefore, and it is with a sense of great privilege that I address you this afternoon. I do not consider the primary ...

Vitamin D: the tricky hormone.

The Association between Depression and Vitamin D and Parathyroid Hormone Levels in Adolescents

Background Depression, a challenging disorder, affects 1–6% of adolescents and early onset often predicts more serious manifestations in later life. Elevated Parathyroid hormone (PTH), parathormone levels have reported among adults with depression. In this study, the roles of 25(OH) D (vitamin D) and parathormone during adolescence, in which the frequency of depression is high, were studied. Ma...

Parathyroid Hormone-Related Peptide and Vitamin D in Phosphocalcic Metabolism for Dromedary Camel

In mammals, phosphocalcic and bone metabolisms are mainly regulated by parathyroid hormone, parathyroid hormone-related peptide (PTHrP) and 1α,25-dihydroxyvitamin D or calcitriol. In camels, circulating levels of calcitriol are 10 times higher than those determined in other ruminants and further increase during early lactation. Calcitriol and parathyroid-related peptide stimulate intestinal abs...